2. Marnie from Girls
Yes, I know. The reason the program is so popular is because of its can't-look-away, that-happened-to-me-the-other-day realism. Unfortunately, people in real life really are primarily concerned with their own problems, and they do shitty things surprisingly regularly - and so do the characters in Girls. Marnie wins though, for sheer uprightness and for how mean she is to Sam.